Which term refers to enlargement of both the liver and spleen?

• A. Hepatomegaly
• B. Splenomegaly
• C. Hepatosplenomegaly
• D. Cholestasis

Answer: (C)

Enlargement of both the liver and the spleen is described by hepatosplenomegaly. The term comes from hepato- meaning liver, spleno- meaning spleen, and megaly meaning enlargement, signaling that both organs are enlarged. If only the liver were enlarged, the term would be hepatomegaly; if only the spleen were enlarged, it would be splenomegaly. Cholestasis, on the other hand, refers to impaired bile flow and is not about organ enlargement.